Maintaining spontaneous ventilation during surgery—a review article

Spontaneous breathing during mechanical ventilation in ARDS

The objective of mechanical ventilation used in the management of Acute Respiratory Distress Syndrome (ARDS) is to ensure adequate tissue oxygenation and alveolar ventilation while limiting the patients’ work of breathing and preventing further damage to the lungs. Although the “partial support” ventilation modes were initially developed to assist weaning or liberation from supported ventilatio...

New modalities for non-invasive positive pressure ventilation: A review article

Efficiency of non-invasive positive pressure ventilation in the treatment of respiratory failure has been shown in many published studies. In this review article, we introduced new modalities of non-invasive ventilation (NIV), clinical settings in which NIV can be used and a practical summary of the latest official guidelines published by the European Respiratory Clinical Practice. Clinical tri...

Clinical review: Respiratory mechanics in spontaneous and assisted ventilation

Pulmonary disease changes the physiology of the lungs, which manifests as changes in respiratory mechanics. Therefore, measurement of respiratory mechanics allows a clinician to monitor closely the course of pulmonary disease. Here we review the principles of respiratory mechanics and their clinical applications. These principles include compliance, elastance, resistance, impedance, flow, and w...

The Breathing-Book Spontaneous breathing during artificial ventilation

Coupling of spontaneous ventilation to heart beat during benzodiazepine sedation.

We have examined in eight male volunteers the effect of midazolam sedation on the relationship between timing of spontaneous ventilations and heart beat. On 2 study days, subjects received either midazolam 0.1 mg kg-1 or saline placebo while recordings were made of ECG and ventilatory impedance pneumography. We observed in all midazolam-treated subjects clear evidence of synchronous or non-sync...